夏丽洁 博士，教授，博士研究生导师
主要研究及招生方向：
研究方向：基于天然产物的药物开发及药理机制研究
招生方向：生物化学与分子生物学专业；生物与医药专业
联系方式：xlj@xju.edu.cn
承担的主要科研项目及奖励：
主持纵向科研项目10余项，其中国家自然科学基金3项，自治区重点研发项目1项，“天山青年计划”青年博士科技人才项目1项。发表SCI论文30余篇，授权国家发明专利4项，获得自治区自然科学优秀论文一等奖1项，三等奖1项。
代表性论文：
1.Pan Y, Fan Z, Yu S, Xia L*, Li J*.ROS-responsive supramolecular antimicrobial peptides-based nanoprodrugs for cervical cancer therapy. Colloids and Surfaces B: Biointerfaces, 2025, 247: 114411.
2.Xve R, Pan Y, Xia L*, Li J*.Non-viral vectors combined delivery of siRNA and anti-cancer drugs to reverse tumor multidrug resistance. Biomedicine & Pharmacotherapy, 2024, 178: 117119.
3.Cai Q, Chen M, Wang B, Wang J, Xia L*, Li J*. Phytosphingosine inhibits the growth of lung adenocarcinoma cells by inducing G2/M phase arrest, apoptosis, and mitochondria-dependent pathway cell death in vitro and in vivo. Chemico-Biological Interactions, 2024,387:110795.
4.Jiang J, Kaysar K, Pan Y, Xia L*, Li J*. A Zeolitic Imidazolate Framework-Based Antimicrobial Peptide Delivery System with Enhanced Anticancer Activity and Low Systemic Toxicity. Pharmaceutics, 2024, 16: 1591.
5.Wang Y, Li J*, Xia L*. Plant-derived natural products and combination therapy in liver cancer, Frontiers in Oncology, 2023, 13: 1116532.
6.He M,Yasin K, Yu S, Xia L*, Li J*. Total Flavonoids in Artemisia absinthium L. and Evaluation of its Anticancer Activity. International Journal of Molecular Sciences, 2023,11:270255.
7.Yasin K, Xia L*, Li J*. Chemical constituents and antitumor mechanisms of Artemisia. Anti- cancer agents in medicinal chemistry, 2022, 22(10):1838-1844.
8.Halike X#, Li J#, Yuan P, Yasheng K, Chen M, Xia L*, Li J*. The petroleum ether extraction of Brassica Rapa L. induces apoptosis of Lung adenocarcinoma cells via mitochondria-dependent pathway. Food & Function, 2021, 12: 100233.
9.He M, Xia L*, Li J*. Potential mechanisms of plant-derived natural products in the treatment of cervical cancer. Biomolecules, 2021, 11: 1539.
10.Xia L*,Teng Q, Chen Q, Zhang F. Preparation and Characterization of Anti-GPC3 Nanobody Against Hepatocellular Carcinoma. International Journal of Nanomedicine, 2020,15:2197-2205.
